Nature is not perfect
One sobering thought concerning our physical world is that despite its grandiose infinity, it is palpably not perfect. Nature, the active agent of the physical world, produces specimens that are not, with all their wonderful design, flawless. Rather, individual cells at all scales deteriorate and die. Humans are all born with defects and accumulate more during their lifetime. Clearly, one can imagine a state of affairs that is more agreeable although we are unable to come up with a consistent logical recipe for it. Which is to be expected, since we are part of Nature and therefore not perfect either.
Since we have that imagination, though, we are bound to seek constant improvement towards perfection. First, in Nature - a lost cause given the hypothesis, but we do indeed, and measurably, move towards perfection or away from it. But the unattainability of the final thing, whatever it means, is so deeply seated in our psyche that we look beyond nature for perfection, in the realm of the spiritual.
In general, we have good cause to follow our imagination. The reality that we have around us, in the 21st century, is overwhelmingly our own making and a product of our imagination - creativity, metasight, etc. But with this success comes the realization of imperfection ("the more we learn, the less we know"), and the search for perfection informs every ramification of knowledge, enterprise, business, spirituality.
It is noteworthy that perfection is not the only human obsession. Communication is another one.